Emily and Judith Pancoast, elderly sisters, are the owners of a priceless dollhouse that is an exact replica of their Victorian home in a small seaside resort near Philadelphia. The dollhouse is inhabited by dolls that the sisters crafted to resemble each member of their family.

On Thanksgiving Day, just before relatives arrive for dinner, Emily Pancoast discovers that the dollhouse dining room table, set in miniature of the real one, is in total disarray and the doll representing their niece Pamela is lying facedown in her dessert plate. When Pamela's death soon follows, the sisters turn to the physician detective, Dr. Andrew Fenimore.