When Odessa Blackburn is three years old her beloved grandmother dies, and so begins her story, set in St. Louis, Missouri, and rural Mississippi. As the fifth born of eight children, Odessa loses her innocence at first when her drunken father sexually abuses her, and then again when she alone witnesses her father taking the life of his own brother.

Fifth Born is Zelda Lockhart's debut novel, lyrically written and powerful in its exploration of how secrets can tear apart lives and families. It is a story of love, longing, and redemption, as Odessa walks away from those whom she believes to be her kin to discover the true meaning of family.