When exhausted workaholic apothecary Colette jumps into a well, instead of dying she finds herself caring for a new patient: Hades, Lord of the Dead. As Colette goes back and forth between her world and the underworld, new patients of every kind arrive daily!

In addition to the underworld, Colette has taken on a temporary role as healer to the celestial realm! When Hades, Lord of the Dead, has concerns about her safety there, he takes action in a surprising way!