In 1938, Lily Renée Wilhelm, a 14-year-old Jewish girl, is living in Vienna when the Nazis march into Austria. After a ship voyage fraught with danger from Nazi torpedoes, teenage Lily reunites with her parents in New York and helps her family earn a living by painting designs on wooden boxes. One day she sees an ad in the paper: a comics publisher is looking for artists. Lily has never drawn comics before, but teaches herself how they work. She is hired to draw the character Senorita Rio, a beautiful spy fighting the Nazis.