In the waning days of the Ottoman Empire, a young Orthodox Jewish woman in the holy city of Jerusalem is expected to marry and produce many sons to help hasten the Messiah's arrival. While the feisty Esther Kaminsky understands her obligations, her artistic talent inspires her to secretly explore worlds outside her religion, to dream of studying in Paris and to believe that God has a special destiny for her. When tragedy strikes her family, Esther views it as a warning from an angry God and suppresses her desires in order to become an obedient "Jerusalem maiden."

But when a surprising opportunity forces itself on to her preordained path, Esther finds her beliefs clashing dangerously with the passions she has staved off her entire life forcing her to confront the most difficult and damning question of all. To whom must she be true, God or herself?